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"More than fifty years before the American Revolution, Boston was in revolt against the tyrannies of the Crown, Puritan Authority, and Superstition. This is the story of a fateful year that prefigured the events of 1776. In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protege; Samuel Adams. During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. "Inoculation" led to vaccination, one of the most profound medical discoveries in history. Public outrag
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